On the basis of recent data from candidate region/gene and genome-wide association studies (GWAS) and their follow-up investigations, the number of genes potentially …
C Zhuo, W Hou, G Li, F Mao, S Li, X Lin, D Jiang… - Progress in Neuro …, 2019 - Elsevier
Due to recent advances in human genomic technologies, there have been explosive interests and extensive research on the genomics of schizophrenia, a severe psychiatric …
S Prasad, P Semwal, S Deshpande, T Bhatia… - Journal of …, 2002 - Springer
Schizophrenia is a severe neuropsychiatric disorder with a polygenic mode of inheritance which is also governed by non-genetic factors. Candidate genes identified on the basis of …
L Hosak - World journal of psychiatry, 2013 - ncbi.nlm.nih.gov
New findings in schizophrenia genetics are based on genome-wide association studies (GWAS), research into DNA copy number variations (CNVs), and endophenotypes. More …
Abstract Purpose of Review This is an era where we have significantly advanced the understanding of the genetic architecture of schizophrenia. In this review, we consider how …
PV Gejman, AR Sanders… - Annual review of …, 2011 - annualreviews.org
The work conducted using genome-wide approaches during the past several years has invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …
I Giegling, L Hosak, R Mössner, A Serretti… - The world journal of …, 2017 - Taylor & Francis
Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general population. The relative contribution of genetic factors has been estimated to be up to 80 …
AR Sanders, HHH Göring, J Duan… - Human molecular …, 2013 - academic.oup.com
Schizophrenia genome-wide association studies (GWAS) have identified common SNPs, rare copy number variants (CNVs) and a large polygenic contribution to illness risk, but …
The range of genetic variation with potential clinical implications in schizophrenia, beyond rare copy number variants (CNVs), remains uncertain. We therefore analyzed genome …