The increasing availability of genotype data in longitudinal population‐and family‐based
samples provides opportunities for using polygenic scores (PGS) to study developmental …

Epidemiological and clinical studies have found associations between depression and
cardiovascular disease risk factors, and coronary artery disease patients with depression …

Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood psychiatric disorder,
with a major genetic component. Here we present a GWAS meta-analysis of ADHD …

Abstract Background and Hypothesis Schizophrenia has been robustly associated with
multiple genetic and environmental risk factors. Childhood adversity is one of the most …

Endophenotypes are heritable and quantifiable traits indexing genetic liability for a disorder.
Here, we examined three potential endophenotypes, working memory function, response …

Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …

Major depressive disorder (MDD) is a common mental disorder generally characterized by
symptoms associated with mood, pleasure and effectiveness in daily life activities. MDD is …

Major depression (MD) is a complex, heterogeneous neuropsychiatric disorder. An early
age at onset of major depression (AAO-MD) has been associated with more severe illness …

Abstract Background and Aims While epidemiological studies support a role for heavy, high‐
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …

Genetically informed drug development and repurposing is an attractive prospect for
improving patient outcomes in psychiatry; however, the effectiveness of these endeavors is …