Numerous studies have examined gene expression profiles in post-mortem human brain
samples from individuals with schizophrenia compared with healthy controls, to gain insight …

Despite the successful identification of several relevant genomic loci, the underlying
molecular mechanisms of schizophrenia remain largely unclear. We developed a …

Genome-wide association studies (GWAS) have proved to be a powerful approach for gene
discovery in schizophrenia; their findings have important implications not just for our …

Schizophrenia is a debilitating mental illness that affects 1% of the population. Despite
intensive study, its molecular etiology remains enigmatic. Like many common diseases …

Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both
the phenotypic and the genetic level. Paradoxically, a modest but consistent positive genetic …

The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …

Functional and structural brain imaging has identified neural and neurotransmitter systems
involved in schizophrenia and their link to cognitive and behavioural disturbances such as …

Schizophrenia (SZ) is a devastating psychiatric condition affecting numerous brain systems.
Recent studies have identified genetic factors that confer an increased risk of SZ and …

Schizophrenia is a psychiatric disorder with onset in late adolescence and unclear etiology
characterized by both positive and negative symptoms, as well as cognitive deficits. To …

Schizophrenia (SZ) is a severe psychotic disorder that is highly heritable and common in the
general population. The genetic heterogeneity of SZ is substantial, with contributions from …