[HTML][HTML] Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders
Psychiatric disorders impose tremendous economic burden on society and are leading
causes of disability worldwide. However, only limited drugs are available for psychiatric …
causes of disability worldwide. However, only limited drugs are available for psychiatric …
[HTML][HTML] Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach
Background Childhood maltreatment is associated with poor mental and physical health.
However, the mechanisms of gene–environment correlations and the potential causal …
However, the mechanisms of gene–environment correlations and the potential causal …
Insights from complex trait fine-mapping across diverse populations
Despite the great success of genome-wide association studies (GWAS) in identifying genetic
loci significantly associated with diseases, the vast majority of causal variants underlying …
loci significantly associated with diseases, the vast majority of causal variants underlying …
[图书][B] Racism, not race: Answers to frequently asked questions
JL Graves, AH Goodman - 2021 - degruyter.com
PREFACE INTRODUCTION Page 1 PREFACE 1. A. Hassan, “Hate-Crimes Violence Hits 16-Year
High, FBI Reports,” New York Times, November 12, 2019, https://www.nytimes.com/2019/11/12/us/hate-crimes-fbi-report …
High, FBI Reports,” New York Times, November 12, 2019, https://www.nytimes.com/2019/11/12/us/hate-crimes-fbi-report …
[HTML][HTML] Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease
J Lake, C Warly Solsberg, JJ Kim, J Acosta-Uribe… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) of Alzheimer's disease are predominantly carried
out in European ancestry individuals despite the known variation in genetic architecture and …
out in European ancestry individuals despite the known variation in genetic architecture and …
Ten challenges for clinical translation in psychiatric genetics
Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …
underlying psychiatric disorders and provided important biological insights into disease …
[HTML][HTML] Genomics and functional genomics of Alzheimer's disease
MI Kamboh - Neurotherapeutics, 2023 - Elsevier
Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disease. Due to
its long clinical course and lack of an effective treatment, AD has become a major public …
its long clinical course and lack of an effective treatment, AD has become a major public …
Algorithm fairness in ai for medicine and healthcare
In the current development and deployment of many artificial intelligence (AI) systems in
healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent …
healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent …
Alteration of the gut microbiome in first-episode drug-naïve and chronic medicated schizophrenia correlate with regional brain volumes
The human gut microbiome plays an important role in the basic neurodevelopmental
processes of the central nervous system and has been implicated in several …
processes of the central nervous system and has been implicated in several …
Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS
WJ Peyrot, AL Price - Nature genetics, 2021 - nature.com
Psychiatric disorders are highly genetically correlated, but little research has been
conducted on the genetic differences between disorders. We developed a new method …
conducted on the genetic differences between disorders. We developed a new method …