We examined the role of common genetic variation in schizophrenia in a genome-wide
association study of substantial size: a stage 1 discovery sample of 21,856 individuals of …

Identifying the molecular alterations that underlie the pathophysiology of critical clinical
features of schizophrenia is an essential step in the rational development of new therapeutic …

Specific cell populations may have unique contributions to schizophrenia but may be missed
in studies of homogenate tissue. Here laser capture microdissection followed by RNA …

Schizophrenia is an etiologically heterogeneous psychiatric disease, which exists in familial
and nonfamilial (sporadic) forms. Here, we examine the possibility that rare de novo copy …

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies
(GWAS) have identified multiple loci that influence the risk of developing schizophrenia …

Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive
deficits and apathy, with a heritability estimated at 73–90%(ref.). Inheritance patterns are …

In a small fraction of patients with schizophrenia or autism, alleles of copy-number variants
(CNVs) in their genomes are probably the strongest factors contributing to the pathogenesis …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

People with schizophrenia are enriched for rare coding variants in genes associated with
neurodevelopmental disorders, particularly autism spectrum disorders and intellectual …

Schizophrenia is a common disorder characterized by psychotic symptoms; diagnostic
criteria have been established 1. Family, twin and adoption studies suggest that both genetic …