Background & Aims The contribution of genetic factors to the pathogenesis of inflammatory
bowel disease (IBD) has been established by twin, targeted-sequencing, and genome-wide …

Over the course of the past decade, genome‐wide association studies (GWAS) have
revolutionised our understanding of complex disease genetics. One of the diseases that has …

Observed inflammatory bowel disease (IBD) familial clustering and increased monozygotic
twin concordance has led to the hypothesis that genetic loci containing IBD susceptibility …

The two main phenotypes of inflammatory bowel disease (IBD)—Crohn's disease (CD) and
ulcerative colitis (UC)—are chronic intestinal inflammatory disorders with a complex genetic …

Inflammatory bowel disease (IBD) describes chronic inflammatory disease of the intestines
and has a variable course; Crohn's disease and ulcerative colitis comprise the two main …

We performed risk assessment for Crohn's disease (CD) and ulcerative colitis (UC), the two
common forms of inflammatory bowel disease (IBD), by using data from the International IBD …

Recent advances have enabled a comprehensive understanding of the genetic architecture
of inflammatory bowel disease (IBD) with over 30 identified and replicated disease loci. The …

Since Tysk et al's pioneering analysis of the Swedish twin registry, twin and family studies
continue to support a strong genetic basis of the inflammatory bowel diseases. The …

Genome-wide association (GWA) studies offer a powerful unbiased method for the
identification of multiple susceptibility genes for complex diseases. Here we report the …

Background Identifying new drug targets for inflammatory bowel disease (IBD) is urgently
needed. The proteome is a major source of therapeutic targets. We conducted a proteome …