Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia

J Bryois, ME Garrett, L Song, A Safi… - Nature …, 2018 - nature.com
Schizophrenia genome-wide association studies have identified> 150 regions of the
genome associated with disease risk, yet there is little evidence that coding mutations …

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

S Raychaudhuri, RM Plenge, EJ Rossin, ACY Ng… - PLoS …, 2009 - journals.plos.org
Translating a set of disease regions into insight about pathogenic mechanisms requires not
only the ability to identify the key disease genes within them, but also the biological …

Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data

P Jia, L Wang, HY Meltzer, Z Zhao - Schizophrenia research, 2010 - Elsevier
Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …

Glutamate networks implicate cognitive impairments in schizophrenia: genome-wide association studies of 52 cognitive phenotypes

K Ohi, R Hashimoto, M Ikeda, H Yamamori… - Schizophrenia …, 2015 - academic.oup.com
Cognitive impairments are a core feature in patients with schizophrenia. These deficits could
serve as effective tools for understanding the genetic architecture of schizophrenia. This …

Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia

MJ Owen, N Craddock… - Archives of general …, 2010 - jamanetwork.com
This article reviews recent genome-wide association studies (GWAS) of schizophrenia and
considers future research directions. Until recently, genome-wide scans for dis-ease risk …