A recent Chinese genome-wide association study found evidence for 58 out of the 128
schizophrenia-associated variants previously discovered in Western samples by the …

Scientifically interesting as well as practically important phenotypes often belong to the
realm of complex traits. To the extent that these traits are hereditary, they are usually 'highly …

Human neuropsychiatric disorders are associated with genetic and environmental factors
affecting the brain, which has been subjected to strong evolutionary pressures resulting in …

Abstract Background and Hypothesis Risk for cannabis use and schizophrenia is influenced
in part by genetic factors, and there is evidence that genetic risk for schizophrenia is …

Abstract Background Obstetric complications (OCs) are key contributors to psychosis risk.
However, it is unclear whether they increase psychosis vulnerability independently of …

The identification of rare variants associated with schizophrenia has proven challenging due
to genetic heterogeneity, which is reduced in founder populations. In samples from the …

Mammalian axonal development begins in embryonic stages and continues postnatally.
After birth, axonal proteomic landscape changes rapidly, coordinated by transcription …

Cardiometabolic disorders have known inflammatory implications, and peripheral measures
of inflammation and cardiometabolic disorders are common in persons with psychotic …

Twin studies can help us understand the relative contributions of genes and environment to
phenotypic trait variation, including attentional and brain activation measures. In terms of …

Functional genomic methods are needed that consider multiple genetically correlated traits.
Here we develop and validate Transcriptome-wide Structural Equation Modeling (T-SEM), a …